Equine herpesvirus type 1 (EHV-1)-induced rearrangements of actin filaments in productively infected primary murine neurons
نویسندگان
چکیده
منابع مشابه
Equine herpesvirus type 1 (EHV-1) replication in primary murine neurons culture.
Equine herpesvirus-1 (EHV-1) infections cause significant economic losses for equine industries worldwide as a result of abortion, respiratory illness, and neurologic disease in all breeds of horses. The occurrence of abortions caused by EHV-1 has repeatedly been confirmed in Poland, but neurological manifestations of the infection have not been described yet. Also it is unknown how the infecti...
متن کاملEquine herpes virus type 1 (EHV-1) and 4 (EHV-4) infections in horses and donkeys in northeastern Turkey
The herpesviruses infections in equides are caused by five different serotypes of viruses, belonging to family Herpesviridae. The goal of this study was to conduct a seroepidemiological investigation of equine herpesvirus type 1 (EHV-1) and type 4 (EHV-4) in horses and donkeys raised in two provinces and their villages in northeastern Turkey. A total of 666 samples from 423 horses and 243 donke...
متن کاملThe Role of the Equine Herpesvirus Type 1 (EHV-1) US3-Encoded Protein Kinase in Actin Reorganization and Nuclear Egress
The serine-threonine protein kinase encoded by US3 gene (pUS3) of alphaherpesviruses was shown to modulate actin reorganization, cell-to-cell spread, and virus egress in a number of virus species. However, the role of the US3 orthologues of equine herpesvirus type 1 and 4 (EHV-1 and EHV-4) has not yet been studied. Here, we show that US3 is not essential for virus replication in vitro. However,...
متن کاملEquine herpesvirus 1 (EHV-1): characterisation of a viral strain isolated from equine plasma in Argentina
Strain "LP-3" of equine herpesvirus 1 (EHV-1), isolated from plasma of horses with clinical signs of rhinopneumonitis, was characterised by cultural, physicochemical, electron microscopic, serological and immunohistochemical studies. This was the first isolation from Argentine horses with respiratory disease. Another strain, SP-1, was isolated in the same laboratory from an aborted fetus in 1980.
متن کاملExperimental infection with equine herpesvirus type 1 (EHV-1) induces chorioretinal lesions
Equine herpesvirus myeloencephalitis (EHM) remains one of the most devastating manifestations of equine herpesvirus type 1 (EHV-1) infection but our understanding of its pathogenesis remains rudimentary, partly because of a lack of adequate experimental models. EHV-1 infection of the ocular vasculature may offer an alternative model as EHV-1-induced chorioretinopathy appears to occur in a signi...
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ژورنال
عنوان ژورنال: Archives of Virology
سال: 2013
ISSN: 0304-8608,1432-8798
DOI: 10.1007/s00705-013-1949-3